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Estrone-d4
$1,125 – $1,800
Products Details
Product Description
– Estrone-d4 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
Web ID
– HY-B0234S2
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C18H18D4O2
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Caupos E, et al. Photodegradation of estrone enhanced by dissolved organic matter under simulated sunlight. Water Res. 2011;45(11):3341-3350.|[3]de Padua Mansur A, et al. Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease. ScientificWorldJournal. 2012;2012:363595.
CAS Number
– 53866-34-5
Molecular Weight
– 274.39
Compound Purity
– 99.0
SMILES
– C[C@@]12[C@](CC([2H])([2H])C2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC([2H])=C(O)C([2H])=C4CC3
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Cancer
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Estrogen Receptor/ERR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
