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Products Details
Product Description
– Ticlopidine-d4 (hydrochloride) is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.
Web ID
– HY-B0153AS
Shipping
– Room temperature
Molecular Formula
– C14H11D4Cl2NS
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Thebault JJ, et al. Effects of ticlopidine, a new platelet aggregation inhibitor in man. Clin Pharmacol Ther. 1975 Oct;18(4):485-90.|[3]Ashida SI, et al. Mode of action of ticlopidine in inhibition of platelet aggregation in the rat. Thromb Haemost. 1979 Apr 23;41(2):436-49.
Molecular Weight
– 304.27
SMILES
– ClC1=C(CN2CC3=C(CC2)SC=C3)C([2H])=C([2H])C([2H])=C1[2H].Cl
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor;Isotope-Labeled Compounds
Pathway
– GPCR/G Protein;Others
Product type
– Isotope-Labeled Compounds
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