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Doxofylline-d6
$190
Only 1000 item(s) left in stock.
Products Details
Product Description
– Doxofylline-d6 is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.
Web ID
– HY-B0004S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C11H8D6N4O4
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Shukla D, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56.
CAS Number
– 1219805-99-8
Molecular Weight
– 272.29
Compound Purity
– 99.0
SMILES
– O=C1C2=C(N=CN2CC3OCCO3)N(C([2H])([2H])[2H])C(N1C([2H])([2H])[2H])=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor;Phosphodiesterase (PDE)
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
