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Roslin 2 (bromide)
SKU
HY-A0280-1 mg
Category Reference compound
Tags Apoptosis;Protein Tyrosine Kinase/RTK, Cancer, FAK;MDM-2/p53
$190
Only 1000 item(s) left in stock.
Products Details
Product Description
– Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator with anticancer effects. Roslin 2 bromide binds FAK, disrupts the binding of FAK and p53[1].
Web ID
– HY-A0280
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H19BrN4
References
– [1]Vita M Golubovskaya, et al. Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth. BMC Cancer. 2013 Jul 11;13:342.
CAS Number
– 29574-21-8
Molecular Weight
– 311.22
Compound Purity
– 99.0
SMILES
– [N@@]12C[N+](C[N@](C3)C1)(C[N@@]3C2)CC4=CC=CC=C4.[Br-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FAK;MDM-2/p53
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.