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Ceruletide
$40 – $420
Products Details
Product Description
– Ceruletide is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts[1].
Web ID
– HY-A0190
Storage Temperature
– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C58H73N13O21S2
References
– [1]Bridger N, et al. Comparison of postprandial and ceruletide serum bile acid stimulation in dogs. J Vet Intern Med. 2008 Jul-Aug;22(4):873-8.|[2]Zarrindast MR, et al. Effects of cholecystokinin receptor agonist and antagonists on morphin dependence in mice. Pharmacol Toxicol. 1995 Dec;77(6):360-4.|[3]Steinle AU, et al. NF-kappaB/Rel activation in cerulein pancreatitis. Gastroenterology. 1999 Feb;116(2):420-30.|[4]Vincent ME, et al. Pharmacology, clinical uses, and adverse effects of ceruletide, a cholecystokinetic agent. Pharmacotherapy. 1982 Jul-Aug;2(4):223-34.
CAS Number
– 17650-98-5
Molecular Weight
– 1352.41
Compound Purity
– 99.96
SMILES
– O=C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@H](C(N)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC(CNC([C@@]([C@H](O)C)([H])NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC2)NC2=O)=O)=O)=O)CC3=CC=C(OS(=O)(O)=O)C=C3)=O)=O)=O)CC4=CNC5=C4C=CC=C5
Clinical Information
– Launched
Research Area
– Metabolic Disease; Cardiovascular Disease; Endocrinology
Solubility
– DMF : 16.67 mg/mL (ultrasonic)|DMSO : 100 mg/mL (ultrasonic)|H2O : 2.5 mg/mL (ultrasonic)
Target
– Cholecystokinin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Peptides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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