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6-Maleimidohexanoic acid N-hydroxysuccinimide ester

$90$260

Products Details

Product Description

– 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates[1].

Web ID

– HY-78961

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C14H16N2O6

References

– [1]Shinya Kida, et al. Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters. Chem Pharm Bull (Tokyo). 2007 Apr;55(4):685-7.|[2]Shinya Kida, et al. Evaluation of synthetic cell-penetrating peptides, Pro-rich peptide and octaargine derivatives, as adenovirus vector carrier. Protein Pept Lett. 2010 Feb;17(2):164-7.

CAS Number

– 55750-63-5

Molecular Weight

– 308.29

Compound Purity

– 99.98

SMILES

– O=C(C=C1)N(CCCCCC(ON2C(CCC2=O)=O)=O)C1=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 230 mg/mL (ultrasonic)

Target

– ADC Linker

Isoform

– Non-cleavable Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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