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Products Details
Product Description
– BCN-HS-PEG2-VA-PABC-SG3199 (Compound 4) is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC)[1]. BCN-HS-PEG2-VA-PABC-SG3199 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Web ID
– HY-47018
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C66H83N9O18S
References
– [1]Patricius Hendrikus Cornelis VAN BERKEL. Pyrrolobenzodiazepine-antibody conjugates. Patent WO2018146199A1.
CAS Number
– 2126805-05-6
Molecular Weight
– 1322.48
SMILES
– O=C(N([C@H]1O)C(C(C(N2[C@@]1([H])CC(C)=C2)=O)=C3)=CC(OCCCCCOC(C=C(N=C[C@@](C4)([H])N(C=C4C)C5=O)C5=C6)=C6OC)=C3OC)OCC(C=C7)=CC=C7NC([C@H](C)NC([C@H](C(C)C)NC(COCCOCCN[S](NC(OC[C@@H]8[C@@]9([H])[C@]8([H])CCC#CCC9)=O)(=O)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
