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DCVC
$420 – $2,520
Products Details
Product Description
– DCVC (S-[(1E)-1,2-dichloroethenyl]–L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures[1][2].
Web ID
– HY-19717
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C5H7Cl2NO2S
References
– [1]Boldenow E, et al. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitro. Reprod Toxicol. 2015 Apr;52:1-6.|[2]Lash LH, et al. Multigenerational study of chemically induced cytotoxicity and proliferation in cultures of human proximal tubular cells. Int J Mol Sci. 2014 Nov 18;15(11):21348-65.
CAS Number
– 13419-46-0
Molecular Weight
– 216.09
Compound Purity
– 99.83
SMILES
– N[C@H](C(O)=O)CS/C(Cl)=CCl
Clinical Information
– Phase 1
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 2.5 mg/mL (ultrasonic)|H2O : 1.034 mg/mL (ultrasonic;warming)
Target
– TNF Receptor
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
