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(+)-SJ733
$228 – $5,040
Products Details
Product Description
– (+)-SJ733 is an anti-malaria agent which can also inhibit Na+-ATPase PfATP4.
Web ID
– HY-19556
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H16F4N4O2
References
– [1]Jimenez-Diaz MB, et al. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5455-62.
CAS Number
– 1424799-20-1
Molecular Weight
– 468.40
Compound Purity
– 99.45
SMILES
– O=C([C@@H](C1=C2C=CC=C1)[C@@H](C3=CC=CN=C3)N(CC(F)(F)F)C2=O)NC4=CC=C(F)C(C#N)=C4
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Na+/K+ ATPase;Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
