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Sulprostone
$350
Only 1000 item(s) left in stock.
Products Details
Product Description
– Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery[1][2][3].
Web ID
– HY-19360
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H31NO7S
References
– [1]S Narumiya, et al. Prostanoid receptors: structures, properties, and functions. Physiol Rev. 1999 Oct;79(4):1193-226.|[2]Jenny Bulgarelli, et al. Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone. Cytotherapy. 2018 Jun;20(6):851-860.|[3]Yifan Shi, et al. Bioanalysis of sulprostone, a prostaglandin E 2 analogue and selective EP 3 agonist, in monkey plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:51-57.
CAS Number
– 60325-46-4
Molecular Weight
– 465.56
Compound Purity
– 99.0
SMILES
– O=C(NS(=O)(C)=O)CCC/C=CC[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)[C@H](O)CC1=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
