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NCT-501
$125 – $1,260
Web ID
– HY-18768
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H32N6O3
References
– [1]Kulsum S et al. Cancer stem cell mediated acquired chemoresistance in head and neck cancer can be abrogated by Aldehydedehydrogenase 1 A1 inhibition.
Mol Carcinog. 2016 Jul 6.|[2]Yang SM, et al. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1(ALDH1A1). J Med Chem. 2015 Aug 13;58(15):5967-5978.
CAS Number
– 1802088-50-1
Molecular Weight
– 416.52
Compound Purity
– 99.84
SMILES
– O=C(N1C)N(C)C2=C(N(CCC(C)C)C(CN3CCN(C(C4CC4)=O)CC3)=N2)C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 3.57 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Aldehyde Dehydrogenase (ALDH)
Isoform
– ALDH1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
