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Rosuvastatin (Calcium) (Standard)
$50 – $120
Products Details
Product Description
– Rosuvastatin (Calcium) (Standard) is the analytical standard of Rosuvastatin (Calcium). This product is intended for research and analytical applications. Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
Web ID
– HY-17504R
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Molecular Formula
– C22H27CaFN3O6S-
CAS Number
– 147098-20-2
Molecular Weight
– 520.61
Compound Purity
– 99.83
SMILES
– O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Cardiovascular Disease; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic)
Target
– Autophagy;Bacterial;HMG-CoA Reductase (HMGCR);Potassium Channel
Pathway
– Anti-infection;Autophagy;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
