Download Files:
L-NMMA (acetate)
$45 – $135
Products Details
Product Description
– L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively.
Web ID
– HY-18732A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C9H20N4O4
References
– [1]Frey C, et al. L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. J Biol Chem. 1994 Oct 21;269(42):26083-91.|[2]Maggi CA, et al. Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum. Br J Pharmacol. 1991 Aug;103(4):1970-2.|[3]Nakamura T, et al. Effect of NG-monomethyl-L-arginine on arcade arterioles of rat spinotrapezius muscles. Am J Physiol. 1991 Jul;261(1 Pt 2):H46-52.
CAS Number
– 53308-83-1
Molecular Weight
– 248.28
Compound Purity
– 98.58
SMILES
– N[C@@H](CCCNC(NC)=N)C(O)=O.O=C(C)O
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease; Cancer
Solubility
– H2O : ≥ 50 mg/mL
Target
– Endogenous Metabolite;NO Synthase
Isoform
– eNOS;iNOS;nNOS
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
