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SYM2206
$132 – $732
Products Details
Product Description
– SYM2206 is a potent and non-competitive AMPA receptor antagonist, with an IC50 of 1.6 μM. SYM2206 blocks Nav1.6-mediated persistent currents[1][2].
Web ID
– HY-18689
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H22N4O3
References
– [1]Bleakman D, et, al. Kainate receptor agonists, antagonists and allosteric modulators. Curr Pharm Des. 2002;8(10):873-85.|[2]Welch NC, et al. Traditional AMPA receptor antagonists partially block Na v1.6-mediated persistent current. Neuropharmacology. 2008 Dec;55(7):1165-71.
CAS Number
– 173952-44-8
Molecular Weight
– 366.41
Compound Purity
– 99.72
SMILES
– O=C(N1N=C(C2=CC=C(N)C=C2)C3=C(C=C4C(OCO4)=C3)C1C)NCCC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– iGluR
Isoform
– AMPA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
