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L-Thyroxine (sodium salt pentahydrate)

$60$78

Products Details

Product Description

– L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1].

Web ID

– HY-18341A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Molecular Formula

– C15H20I4NNaO9

References

– [1]Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65(3):317-323.|[2]Corriveau S, et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2(4):144-149.

CAS Number

– 6106-07-6

Molecular Weight

– 888.93

Compound Purity

– 99.38

SMILES

– N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O[Na])=O.O.O.O.O.O

Clinical Information

– Launched

Research Area

– Endocrinology; Cancer

Solubility

– DMSO : ≥ 28 mg/mL|H2O : < 0.1 mg/mL

Target

– Endogenous Metabolite;Thyroid Hormone Receptor

Isoform

– Human Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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