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Esomeprazole (sodium)
$49 – $325
Products Details
Product Description
– Esomeprazole sodium ((S)-Omeprazole sodium) is a potent and orally active proton pump inhibitor. Esomeprazole reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases[4]. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].
Web ID
– HY-17023
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Molecular Formula
– C17H18N3NaO3S
References
– [1]Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46.|[2]Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16.|[3]Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.|[4]Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
CAS Number
– 161796-78-7
Molecular Weight
– 367.40
Compound Purity
– 99.35
SMILES
– O=[S@](C1=NC2=CC(OC)=CC=C2N1[Na])CC3=NC=C(C)C(OC)=C3C
Clinical Information
– Launched
Research Area
– Endocrinology; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|Ethanol : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Bacterial;Proton Pump
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
