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Ochromycinone
$181 – $3,400
Products Details
Product Description
– Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity[1][2].
Web ID
– HY-18061
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H14O4
References
– [1]Song H, et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4700-5.|[2]Nataliya I. Kalinovskaya, et al. New Angucyclinones from the Marine Mollusk Associated Actinomycete Saccharothrix espanaensis An 113. Natural product communications. 2008, 3(10):1611-1616.
CAS Number
– 111540-00-2
Molecular Weight
– 306.31
Compound Purity
– 99.11
SMILES
– CC(CC1=O)CC2=C1C3=C(C=C2)C(C4=C(O)C=CC=C4C3=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)
Target
– Bacterial;STAT
Isoform
– STAT3
Pathway
– Anti-infection;JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
