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Products Details
Product Description
– Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator with partial agonist properties.
Web ID
– HY-16728
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C18H31N5O6
References
– [1]Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11.
CAS Number
– 117928-94-6
Molecular Weight
– 413.47
Compound Purity
– 99.49
SMILES
– O=C(N(CCC1)[C@@H]1C(N[C@H](C(N)=O)[C@H](O)C)=O)[C@H](CCC2)N2C([C@@H](N)[C@H](O)C)=O
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 32 mg/mL
Target
– iGluR
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
