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Products Details
Product Description
– FABP4-IN-3 (compound C3) is a highly selective FABP4 inhibitor (FABP4 Ki = 25 ± 3a nM, FABP3 Ki = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease[1].
Web ID
– HY-163032
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C20H16ClNO2
References
– [1]Yechun Xu, et al. Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3. European Journal of Medicinal Chemistry. 2023，Journal Pre-proof.
Molecular Weight
– 337.80
SMILES
– CC1=CC=CC(NC2=CC=CC(Cl)=C2C3=CC=CC=C3)=C1C(O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– FABP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
