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Products Details
Product Description
– α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor (IC50: 4.32 μM) with acute hypoglycemic activity. α-Glucosidase-IN-43 exhibits safety and in vivo efficacy, is nontoxic to normal mouse fibroblasts, and is able to rescue streptozotocin (HY-13753)-induced diabetic rats. α-Glucosidase-IN-43 can be used to study postprandial hyperglycemia in diabetic patients[1].
Web ID
– HY-163005
Shipping
– Room temperature
Molecular Formula
– C27H31N3O4
References
– [1]Singh A et al. Discovery of triazole tethered thymol/carvacrol-coumarin hybrids as new class of α-glucosidase inhibitors with potent in vivo antihyperglycemic activities. Eur J Med Chem. 2023 Nov 15;263:115948.
Molecular Weight
– 461.55
SMILES
– O=C1C=C(OCCCCCN2N=NC(COC3=CC(C(C)C)=CC=C3C)=C2)C4=C(O1)C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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