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MC-DOXHZN (hydrochloride)
$160 – $280
Products Details
Product Description
– MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties[1].
Web ID
– HY-16261B
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C37H43ClN4O13
References
– [1]Sevim Rollas, et al. Hydrazone, Amide, Carbamate, Macromolecular and Other Prodrugs of Doxorubicin. The Open Drug Delivery Journal, 2008, 2, 77-85.
CAS Number
– 480998-12-7
Molecular Weight
– 787.21
Compound Purity
– 98.0
SMILES
– [H][C@@]1(O[C@H]2C[C@@](/C(CO)=NNC(CCCCCN3C(C=CC3=O)=O)=O)(O)CC(C2=C4O)=C(O)C5=C4C(C6=C(OC)C=CC=C6C5=O)=O)O[C@@H](C)[C@@H](O)[C@@H](N)C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Drug-Linker Conjugates for ADC;Topoisomerase
Isoform
– Daunorubicins/Doxorubicins;Topo II
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
