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Sparsentan
$165 – $1,375
Products Details
Product Description
– Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1].
Web ID
– HY-17621
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C32H40N4O5S
References
– [1]Murugesan N, et al. Dual angiotensin II and endothelin A receptor antagonists: synthesis of 2′-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokinetics. J Med Chem. 2005 Jan 13;48(1):171-9.
CAS Number
– 254740-64-2
Molecular Weight
– 592.75
Compound Purity
– 99.17
SMILES
– O=S(C1=CC=CC=C1C2=CC=C(CN3C(CCCC)=NC4(CCCC4)C3=O)C=C2COCC)(NC5=NOC(C)=C5C)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Angiotensin Receptor;Endothelin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
