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VER-50589
SKU
HY-15984-1 mg
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Apoptosis;HSP, Cancer
$60 – $250
Products Details
Product Description
– VER-50589 is a Hsp90 inhibitor, with an IC50 of 21 nM and a Kd of 4.5 nM.
Web ID
– HY-15984
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H17ClN2O5
References
– [1]Sharp SY, et al. Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues. Mol Cancer Ther. 2007 Apr;6(4):1198-211.
CAS Number
– 747413-08-7
Molecular Weight
– 388.80
Compound Purity
– 99.97
SMILES
– O=C(C1=NOC(C2=CC(Cl)=C(O)C=C2O)=C1C3=CC=C(OC)C=C3)NCC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 48 mg/mL
Target
– Apoptosis;HSP
Isoform
– HSP90
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.