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CCT007093
$51 – $1,375
Products Details
Product Description
– CCT007093 is an effective protein phosphatase 1D (PPM1D Wip1) inhibitor. Wip1 inhibition can activate the mTORC1 pathway and enhance hepatocyte proliferation after hepatectomy[1][2].
Web ID
– HY-15880
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H12OS2
References
– [1]Lingling Zhang, et al. Inhibition of wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mammalian target of rapamycin. Hepatology. 2015 Jun;61(6):2030-41.|[2]S Rayter, et al. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. Oncogene. 2008 Feb 14;27(8):1036-44.
CAS Number
– 176957-55-4
Molecular Weight
– 272.39
Compound Purity
– 98.01
SMILES
– O=C1/C(CC/C1=CC2=CC=CS2)=C/C3=CC=CS3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMF : 3.33 mg/mL (ultrasonic)|DMSO : ≥ 2.8 mg/mL
Target
– Apoptosis;Autophagy;Phosphatase
Pathway
– Apoptosis;Autophagy;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
