Download Files:
CW-069
$62 – $935
Products Details
Product Description
– CW-069 is an allosteric inhibitor of microtubule motor protein HSET with an IC50 of 75 μM.
Web ID
– HY-15857
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H21IN2O3
References
– [1]Watts CA, et al. Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes. Chem Biol. 2013 Nov 21;20(11):1399-410.
CAS Number
– 1594094-64-0
Molecular Weight
– 500.33
Compound Purity
– 98.99
SMILES
– O=C(NC1=CC=C(I)C=C1C(O)=O)[C@@H](NCC2=CC=CC=C2)CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 52 mg/mL
Target
– Kinesin
Isoform
– Kinesin-14
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
