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Products Details
Product Description
– hDHODH-IN-14 (compound 14) is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an IC50 of 0.469 μM[1].
Web ID
– HY-157153
Shipping
– Room temperature
Molecular Formula
– C21H14N2O3S
References
– [1]Xiaoli Ren, et al. Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking. Chem Biol Drug Des. 2023 Nov 5.
CAS Number
– 881826-17-1
Molecular Weight
– 374.41
SMILES
– O=C(C1=C(/N=C(NC/2=O)SC2=C/C3=CC=CC4=C3C=CC=C4)C=CC=C1)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
