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Products Details
Product Description
– PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].
Web ID
– HY-156445
Shipping
– Room temperature
Molecular Formula
– C28H30N8O3S
References
– [1]Yang Yang, et al. Discovery of novel potent PI3K/mTOR dual-target inhibitors based on scaffold hopping: Design, synthesis, and antiproliferative activity. Arch Pharm (Weinheim). 2023 Oct 15:e2300403.
CAS Number
– 2919684-77-6
Molecular Weight
– 558.65
SMILES
– O=C(NC1=CC=C(C2=NC(N3CCOCC3)=NC(C4=CC=C(CN5CCOCC5)S4)=N2)C=C1)NC6=CC=CN=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR;PI3K
Isoform
– mTOR;PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
