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Products Details
Product Description
– GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC50=2.23 μM)[1].
Web ID
– HY-156287
Shipping
– Room temperature
Molecular Formula
– C22H18N4
References
– [1]Zheng J, et al. Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase. J Med Chem. 2019 Feb 14;62(3):1218-1230.
CAS Number
– 796079-91-9
Molecular Weight
– 338.41
SMILES
– C1(C2=NC3=C(C(N4CC5=C(CC4)C=CC=C5)=N2)C=CC=C3)=CN=CC=C1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
