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Products Details
Product Description
– HDAC-IN-61 (compound 12k) is a potent and orally active HDAC inhibitor. HDAC-IN-61 has anticancer active with an IC50 value of 30 nM for Bel-7402 cell. HDAC-IN-61 can be used in research of cancer[1].
Web ID
– HY-155695
Shipping
– Room temperature
Molecular Formula
– C28H27N3O5
References
– [1]Lai Z, et, al. Discovery of Novel 1,2,3,4-Tetrahydrobenzofuro[2,3-c]pyridine Histone Deacetylase Inhibitors for Efficient Treatment of Hepatocellular Carcinoma. J Med Chem. 2023 Aug 10;66(15):10791-10807.
Molecular Weight
– 485.53
SMILES
– O=C([C@@H](N1CCC(C2=CC=C(C=C2O3)OC)=C3C1)CC4=CC=CC=C4)NC5=CC=C(C=C5)C(NO)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
