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Products Details
Product Description
– HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. HMG-CoA Reductase-IN-1has high HMGR inhibitory activity and OATP1B1 affinity with pIC50 and pKm values of 8.54 and 1.98, respectively. HMG-CoA Reductase-IN-1 can be used for the research of hypercholesterolemia[1].
Web ID
– HY-155668
Shipping
– Room temperature
Molecular Formula
– C27H29N3O7
References
– [1]Samizo S, et al. Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors. ACS Omega. 2023 Jul 18;8(30):27247-27255.
Molecular Weight
– 507.54
SMILES
– OC1=CC=C(C=C1)NC(C2=C(/C=C/[C@H](C[C@@H](O)CC(O)=O)O)C(C(C)C)=NC(C3=CC=C(C=C3)O)=N2)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– HMG-CoA Reductase (HMGCR)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
