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BT424
$350 – $3,000
Products Details
Product Description
– BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].
Web ID
– HY-155657
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H15BCl2N2O2
References
– [1]Chen M, et al. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nat Commun. 2023 Jul 18;14(1):4297.
CAS Number
– 2755180-37-9
Molecular Weight
– 421.08
SMILES
– ClC1=CC2=C(OC(C(C3=NOB(C4=CC=CC=C4)N3)=C2)C5=CC=CC=C5)C(Cl)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Src
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
