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Products Details
Product Description
– M867 is a selective and reversible inhibitor of caspase-3 with an IC50 of 1.4 nM and Ki of 0.7 nM. M867 has anti apoptotic activity[1].
Web ID
– HY-155613
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H43N7O6
References
– [1]Han Y, et.al. Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1173-80.
CAS Number
– 680999-39-7
Molecular Weight
– 561.67
SMILES
– O=C1N(C=C(N=C1NCC2=NON=C2C)C(C)(C)C)[C@H](C(N[C@H](C(CN(CCCCC)C)=O)CC(O)=O)=O)CC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Caspase
Isoform
– Caspase 3
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
