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Products Details
Product Description
– Cathepsin C-IN-6 (compound 2) is a E-64c-hydrazideas based inhibitor of cathepsin C with anti-inflammatory activity. Cathepsin C-IN-6 inhibts activation of neutrophil elastase，exhibits potential efficacy in inflammatory diseases with high neutrophil load (e.g.，chronic obstructive pulmonary disease)[1].
Web ID
– HY-155611
Shipping
– Room temperature
Molecular Formula
– C24H35N5O4.xC2HF3O2
References
– [1]Tromsdorf N, et al. E‐64c‐hydrazide based cathepsin C inhibitors: Optimizing the interactions with the S1’‐S2’area[J]. ChemMedChem, 2023: e202300218..
Molecular Weight
– N/A
SMILES
– CCCCNNC([C@@H]1O[C@H]1C(N[C@H](C(NCCC2=CNC3=C2C=CC=C3)=O)CCCC)=O)=O.O=C(O)C(F)(F)F.[x]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Cathepsin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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