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BMS-817399
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– BMS-817399 is a potent, selective, and orally bioavailable CCR1 antagonist. BMS-817399 exhibits CCR1 binding affinity and chemotaxis inhibition potencies of 1 and 6 nM (IC50), respectively. BMS-817399 can be used for the research of rheumatoid arthritis[1].
Web ID
– HY-15546
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H36ClN3O4
References
– [1]Santella JB 3rd, et al. Discovery of the CCR1 antagonist, BMS-817399, for the treatment of rheumatoid arthritis. J Med Chem. 2014;57(18):7550-7564.
CAS Number
– 1202400-18-7
Molecular Weight
– 454.00
SMILES
– O[C@@](CCN1C([C@@H](C(C)C)NC(NCC(C)(O)C)=O)=O)(C(C=C2)=CC=C2Cl)C(C)(C1)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CCR
Isoform
– CCR1
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
