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AZD-4818
$250 – $2,650
Products Details
Product Description
– AZD-4818 is a potent antagonist of chemokine CCR1. AZD-4818 can be used for researching chronic obstructive pulmonary disease (COPD) [1].
Web ID
– HY-15545
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C27H32Cl2N2O7
References
– [1]Norman P. AZD-4818, a chemokine CCR1 antagonist: WO2008103126 and WO2009011653. Expert Opin Ther Pat. 2009;19(11):1629-1633.
CAS Number
– 1003566-93-5
Molecular Weight
– 567.46
Compound Purity
– 98.78
SMILES
– CNC(C(C=C(C(OC(C)(C)C(O)=O)=C1)Cl)=C1OC[C@@H](O)CN2CCC3(CC2)OC4=CC=C(Cl)C=C4C3)=O
Clinical Information
– Phase 2
Research Area
– Endocrinology; Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic;adjust pH to 2 with HCl)
Target
– CCR
Isoform
– CCR1
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
