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Products Details
Product Description
– Tubulin polymerization-IN-53 (compound 4b) is an inhibitor of β-tubulin polymerization. Tubulin polymerization-IN-53 can arrest the cell cycle at the G2/M stage. Tubulin polymerization-IN-53 has antiproliferative efficacy against the MDA-MB-231 cell line with an IC50 value of 3.24 μM[1].
Web ID
– HY-155350
Shipping
– Room temperature
Molecular Formula
– C19H18ClNO6
References
– [1]Eman Fayad, et al. Novel Acrylate-Based Derivatives: Design, Synthesis, Antiproliferative Screening, and Docking Study as Potential Combretastatin Analogues. ACS Omega. 2023, 8,41.
Molecular Weight
– 391.80
SMILES
– O=C(C1=CC(OC)=C(C(OC)=C1)OC)N/C(C(O)=O)=CC2=CC=C(C=C2)Cl
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
