Download Files:
Products Details
Product Description
– Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC50 of 5.05 μM in SK-Mel-28 cells. Tubulin polymerization-IN-50 induces the cell cycle arrest in the G2/M phase[1].
Web ID
– HY-155314
Shipping
– Room temperature
Molecular Formula
– C24H20FN3O3
References
– [1]Laxmikeshav K et al. Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and in vitro cytotoxicity studies [published online ahead of print, 2023 Oct 3]. Bioorg Med Chem Lett. 2023;96:129494.
Molecular Weight
– 417.43
SMILES
– COC1=CC(C2=NC3=C(N2)C=CC(F)=C3)=CC=C1OCC(N4CCC5=C4C=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
