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Products Details
Product Description
– MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. MMP-13-in-1 can be used for atherosclerosis research[1].
Web ID
– HY-154868
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H16F3N3O3
References
– [1]Buchler A, et al. Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis. J Med Chem. 2023 May 25;66(10):6682-6696.
CAS Number
– 2925249-49-4
Molecular Weight
– 391.34
SMILES
– FC(C(C)=C1)=CC=C1CNC(C2=NC3=C(C(N2)=O)C(OCCF)=C(C=C3)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– MMP
Isoform
– MMP-13
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
