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UCL-TRO-1938
$270 – $2,250
Products Details
Product Description
– UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and neural regeneration effects[1].
Web ID
– HY-154848
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C27H32N6O
References
– [1]Grace Q Gong, et al. A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature. 2023 Jun;618(7963):159-168.
CAS Number
– 2919575-27-0
Molecular Weight
– 456.58
Compound Purity
– 99.56
SMILES
– O=C(C)N1C2=C(CC1)C=CC=C2NC3=CC(NC4=CC=C(N5CCN(CC5)CC)C=C4)=NC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
