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Products Details
Product Description
– PB089 is a Drug-liker containing a PEG unit and a cleavable linker attached to Exatecan[1].
Web ID
– HY-153947
Shipping
– Room temperature
Molecular Formula
– C90H133FN12O32
References
– [1]Xiao, S, et, al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2.|[2]Xiao, S, et, al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2.
CAS Number
– 2892336-54-6
Molecular Weight
– 1914.08
SMILES
– O=C(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCCCCN(C2=O)C(C=C2)=O)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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