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Ac-VLPE-FMK
$380 – $1,200
Products Details
Product Description
– Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness[1][2].
Web ID
– HY-153614
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C25H41FN4O7
References
– [1]Rudzińska M, et, al. Cysteine Cathepsins Inhibition Affects Their Expression and Human Renal Cancer Cell Phenotype. Cancers (Basel). 2020 May 21;12(5):1310.|[2]Citarella A, et, al. Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry. Molecules. 2020 Sep 3;25(17):4031.
CAS Number
– 2679825-27-3
Molecular Weight
– 528.61
Compound Purity
– 99.0
SMILES
– O=C(N(CCC1)[C@@H]1C(N[C@H](C(CF)=O)CCC(OC)=O)=O)[C@H](CC(C)C)NC([C@H](C(C)C)NC(C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Cathepsin
Isoform
– Cathepsin B;Cathepsin L
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
