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GGFG-amide-glycol-amide-Exatecan

$442$3,421

Products Details

Product Description

– GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan (HY-13631) derivative and can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

Web ID

– HY-153600

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Molecular Formula

– C43H47FN8O11

References

– [1]Marija VRLJIC, et al. Exatecan derivatives and antibody-drug conjugates thereof. WO2022236136A1.

CAS Number

– 2866301-18-8

Molecular Weight

– 870.88

Compound Purity

– 98.73

SMILES

– NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NCOCCOC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Drug-Linker Conjugates for ADC;Topoisomerase

Pathway

– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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