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PRMT5-IN-28

SKU HY-153421-Get quote Category Tags , ,

Products Details

Product Description

– PRMT5-IN-28 (compound 36) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) enzyme. Protein arginine methylation is a common post-translational modification involved in gene transcription, mRNA splicing, DNA repair, protein cellular localization, cell fate determination and signal transduction, etc. Abnormal PRMT5 can promote cancer cell proliferation, resist apoptosis, enhance invasion and metastasis, and affect immune escape[1].

Web ID

– HY-153421

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C18H19ClN4O5

CAS Number

– 2242753-66-6

Molecular Weight

– 406.82

SMILES

– O[C@H]([C@@H]1O)[C@@H](O[C@]1([H])[C@@H](C(C=C2)=CC=C2Cl)O)N3C(NC=N/C4=NOC)=C4C=C3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Histone Methyltransferase

Isoform

– PRMT5

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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