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(S)-BAY 2965501

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Products Details

Product Description

– (S)-BAY 2965501 is the left-handed isomer of BAY 2965501 (HY-153343). BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1].

Web ID

– HY-153343A

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-Kinase/protease

Molecular Formula

– C20H19FN4O3S

References

– [1]Schubert N, et al. Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGK味 inhibitor BAY2965501 in clinical trials. Cancer Research, 2023, 83(7_Supplement): 2116-2116.

CAS Number

– 2732902-09-7

Molecular Weight

– 414.45

Compound Purity

– 99.88

SMILES

– NC([C@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– DGK;ERK

Pathway

– MAPK/ERK Pathway;Metabolic Enzyme/Protease;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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