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Products Details
Product Description
– Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a coupling compound that can be used for the synthesis of ADC. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan synthesized ADC shows good antitumor activity in vitro and in vivo[1].
Web ID
– HY-153067
Shipping
– Room temperature
Molecular Formula
– C55H60FN9O13
References
– [1]Yi Zhu, et al. Camptothecin drug and antibody conjugate thereof. Patent WO2022056696A1.
CAS Number
– 2578019-72-2
Molecular Weight
– 1074.12
SMILES
– O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)NCC(NCC(N[C@@H](CC3=CC=CC=C3)C(NCC(NCO[C@@H](C)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
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