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Cabergoline
$96 – $558
Products Details
Product Description
– Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
Web ID
– HY-15296
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C26H37N5O2
References
– [1]Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21.|[2]Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271.
CAS Number
– 81409-90-7
Molecular Weight
– 451.60
Compound Purity
– 99.86
SMILES
– C=CCN1[C@@]2([H])[C@@](C[C@H](C1)C(N(CCCN(C)C)C(NCC)=O)=O)([H])C3=CC=CC4=C3C(C2)=CN4
Clinical Information
– Launched
Research Area
– Endocrinology; Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Autophagy;Dopamine Receptor
Isoform
– D2 Receptor;D3 Receptor
Pathway
– Autophagy;GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
