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Products Details
Product Description
– CB2R/FAAH modulator-1 is a cannabinoid type 2 receptor (CB2R) full agonist with Kis of 14.8 nM and 241.3 nM for CB2R and CB1R, respectively. CB2R/FAAH modulator-1 is a fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 4 μM. CB2R/FAAH modulator-1 decreases pro-inflammatory and increases anti-inflammatory cytokines production[1].
Web ID
– HY-152251
Shipping
– Room temperature
Molecular Formula
– C24H27NO2
References
– [1]Francesca Intranuov, et al. Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. J Med Chem. 2023 Jan 12;66(1):235-250.
CAS Number
– 928892-60-8
Molecular Weight
– 361.48
SMILES
– O=C(C1=C(OCC2=CC=CC=C2)C=CC=C1)NC3(C[C@H](C4)C5)C[C@@H]4C[C@@H]5C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Cannabinoid Receptor;FAAH
Isoform
– CB1;CB2
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
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