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Products Details
Product Description
– BPDA2 is a highly selective and competitive active site SHP2 inhibitor with IC50s of 92.0 nM, 33.39 μM, 40.71 μM for SHP2, SHP1, SHP1B, respectively. DBDA2 downregulates mitogenic and cell survival signaling and RTK expression. BPDA2 suppresses SHP2 mediated signaling and breast cancer cell phenotypes[1].
Web ID
– HY-152208
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H30O5
References
– [1]Dhanaji M Lade, et al. Design and synthesis of improved active-site SHP2 inhibitors with anti-breast cancer cell effects. Eur J Med Chem. 2023 Feb 5;247:115017.
CAS Number
– 2907659-86-1
Molecular Weight
– 398.49
SMILES
– CCCCCCCCCOC1=CC=C(C=C1C(O)=O)C2=CC=C(C=C2)CC(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SHP2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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