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α-Glucosidase-IN-22

$270$900

Products Details

Product Description

– α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research[1].

Web ID

– HY-152158

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C14H11N3O2S

References

– [1]Sardar Ali, et al. Novel 5-(Arylideneamino)-1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7(48):43468-43479.

CAS Number

– 2870693-28-8

Molecular Weight

– 285.32

Compound Purity

– 99.13

SMILES

– S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Glucosidase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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