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Products Details
Product Description
– SB26019 is a potent anti-neuroinflammatory agent. SB26019 regulates NF-κB activation by inducing monomeric α-tubulin formation. SB26019-induced α-tubulin monomer inhibits p65 translocation[1].
Web ID
– HY-152089
Shipping
– Room temperature
Molecular Formula
– C24H20O4
References
– [1]Junhyeong Yim, et al. Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin-p65 interaction. Exp Mol Med. 2022 Dec 12;1-10.
CAS Number
– 1233078-90-4
Molecular Weight
– 372.41
SMILES
– COC1=CC=C2C(C3=C4OC5=C(C4=CC=C3)C=CC=C5)=CC(C)(OC2=C1O)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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